There are a few things that need improving.
First of all, Amy's sprite is blurry.
And you have quite a few grammer mistakes.
Try not to repeat the same moves over again in the same combination.
Make the fights longer with more movement rather than them standing in one area.
Try not to blur the scene with Aeon - even if it is as an effect of the rain. It looks unaffective.
Don't mix up genesis sprites with other styles.
Make them move while they talk rather than a picture and some text.
And last of all, make the intro shorter. Don't use the whole thing because it become boring.

Other than that, it was really fun to see the plot unravel and the fights.

Woah. Awesome! It's pretty cool. Do you mind giving me a link to the backgrounds that you used?

COOL! But why powerpuff girls?

oh man! i got 13765 but the game stopped loading!!!